Effects of Genetic Variation in Protease Activated Receptor 4 after an Acute Coronary Syndrome: Analysis from the TRACER trial

Variation in platelet response to thrombin may affect the safety and efficacy of PAR antagonism. The Thr120 variant of the common single nucleotide polymorphism (SNP) rs773902 in the protease-activated receptor (PAR) 4 gene is associated with higher platelet aggregation compared to the Ala120 varian...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood Cells Mol Dis
Egile Nagusiak: Tricoci, Pierluigi, Neely, Megan, Whitley, Michael J., Edelstein, Leonard C., Simon, Lukas M., Shaw, Chad, Fortina, Paolo, Moliterno, David J., Armstrong, Paul W., Aylward, Philip, White, Harvey, Van de Werf, Frans, Jennings, Lisa K., Wallentin, Lars, Held, Claes, Harrington, Robert A, Mahaffey, Kenneth W., Bray, Paul F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097632/
https://ncbi.nlm.nih.gov/pubmed/30055940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2018.07.004
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