Effects of Genetic Variation in Protease Activated Receptor 4 after an Acute Coronary Syndrome: Analysis from the TRACER trial

Variation in platelet response to thrombin may affect the safety and efficacy of PAR antagonism. The Thr120 variant of the common single nucleotide polymorphism (SNP) rs773902 in the protease-activated receptor (PAR) 4 gene is associated with higher platelet aggregation compared to the Ala120 varian...

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Detalhes bibliográficos
Publicado no:Blood Cells Mol Dis
Main Authors: Tricoci, Pierluigi, Neely, Megan, Whitley, Michael J., Edelstein, Leonard C., Simon, Lukas M., Shaw, Chad, Fortina, Paolo, Moliterno, David J., Armstrong, Paul W., Aylward, Philip, White, Harvey, Van de Werf, Frans, Jennings, Lisa K., Wallentin, Lars, Held, Claes, Harrington, Robert A, Mahaffey, Kenneth W., Bray, Paul F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097632/
https://ncbi.nlm.nih.gov/pubmed/30055940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2018.07.004
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