Persistent synovial inflammation plays important roles in persistent pain development in the rat knee before cartilage degradation reaches the subchondral bone

BACKGROUND: The major complaint of knee osteoarthritis (OA) is persistent pain. Unlike acute inflammatory pain, persistent pain is usually difficult to manage since its pathology is not fully understood. To elucidate the underlying mechanisms of persistent pain, we established 2 different inflammati...

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Detalhes bibliográficos
Publicado no:BMC Musculoskelet Disord
Main Authors: Hoshino, Takashi, Tsuji, Kunikazu, Onuma, Hiroaki, Udo, Mio, Ueki, Hiroko, Akiyama, Masako, Abula, Kahaer, Katagiri, Hiroki, Miyatake, Kazumasa, Watanabe, Toshihumi, Sekiya, Ichiro, Koga, Hideyuki, Muneta, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097215/
https://ncbi.nlm.nih.gov/pubmed/30115046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-018-2221-5
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