Persistent synovial inflammation plays important roles in persistent pain development in the rat knee before cartilage degradation reaches the subchondral bone

BACKGROUND: The major complaint of knee osteoarthritis (OA) is persistent pain. Unlike acute inflammatory pain, persistent pain is usually difficult to manage since its pathology is not fully understood. To elucidate the underlying mechanisms of persistent pain, we established 2 different inflammati...

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Dades bibliogràfiques
Publicat a:BMC Musculoskelet Disord
Autors principals: Hoshino, Takashi, Tsuji, Kunikazu, Onuma, Hiroaki, Udo, Mio, Ueki, Hiroko, Akiyama, Masako, Abula, Kahaer, Katagiri, Hiroki, Miyatake, Kazumasa, Watanabe, Toshihumi, Sekiya, Ichiro, Koga, Hideyuki, Muneta, Takeshi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097215/
https://ncbi.nlm.nih.gov/pubmed/30115046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-018-2221-5
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