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Homologous recombination deficiency in ovarian cancer: a review of its epidemiology and management
Ovarian cancer patients with homologous recombination deficiencies exhibit specific clinical behaviors, and improved responses to treatments, such as platinum-based chemotherapy and poly (ADP-ribose) polymerase (PARP) inhibitors, have been observed. Germline mutations in the BRCA 1/2 genes are the m...
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| Опубликовано в: : | Clinics (Sao Paulo) |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6096977/ https://ncbi.nlm.nih.gov/pubmed/30133561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6061/clinics/2018/e450s |
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