Homologous recombination deficiency in ovarian cancer: a review of its epidemiology and management

Ovarian cancer patients with homologous recombination deficiencies exhibit specific clinical behaviors, and improved responses to treatments, such as platinum-based chemotherapy and poly (ADP-ribose) polymerase (PARP) inhibitors, have been observed. Germline mutations in the BRCA 1/2 genes are the m...

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Sparad:
Bibliografiska uppgifter
I publikationen:Clinics (Sao Paulo)
Huvudupphovsmän: da Cunha Colombo Bonadio, Renata Rodrigues, Fogace, Rodrigo Nogueira, Miranda, Vanessa Costa, Diz, Maria del Pilar Estevez
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2018
Ämnen:
Review Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096977/
https://ncbi.nlm.nih.gov/pubmed/30133561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6061/clinics/2018/e450s
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