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Exploiting the Prevalence of Homologous Recombination Deficiencies in High-Grade Serous Ovarian Cancer

High-grade serous ovarian cancer (HGSOC) remains the most lethal gynecologic cancer in the United States. Genomic analysis revealed roughly half of HGSOC display homologous repair deficiencies. An improved understanding of the genomic and somatic mutations that influence DNA repair led to the develo...

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Detalles Bibliográficos
Publicado en:Cancers (Basel)
Main Authors: Bouberhan, Sara, Philp, Lauren, Hill, Sarah, Al-Alem, Linah F., Rueda, Bo
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7281458/
https://ncbi.nlm.nih.gov/pubmed/32403357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12051206
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