Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines

With an ongoing threat posed by circulating zoonotic strains, new strategies are required to prepare for the next emergent coronavirus (CoV). Previously, groups had targeted conserved coronavirus proteins as a strategy to generate live attenuated vaccine strains against current and future CoVs. With...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Menachery, Vineet D., Gralinski, Lisa E., Mitchell, Hugh D., Dinnon, Kenneth H., Leist, Sarah R., Yount, Boyd L., McAnarney, Eileen T., Graham, Rachel L., Waters, Katrina M., Baric, Ralph S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096805/
https://ncbi.nlm.nih.gov/pubmed/29976657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00710-18
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