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Recurrent Loss of APOBEC3H Activity during Primate Evolution

Genes in the APOBEC3 family encode cytidine deaminases that provide a barrier against viral infection and retrotransposition. Of all the APOBEC3 genes in humans, APOBEC3H (A3H) is the most polymorphic: some genes encode stable and active A3H proteins, while others are unstable and poorly antiviral....

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Garcia, Erin I., Emerman, Michael
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096791/
https://ncbi.nlm.nih.gov/pubmed/29925657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00971-18
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