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Design, synthesis, and biological evaluation of m-amidophenol derivatives as a new class of antitubercular agents

A series of m-amidophenol derivatives (6a–6l, 7a–7q, 9a, 9b, 12a–12c, 14 and 15) were designed and synthesized. Their antitubercular activities were evaluated in vitro against M. tuberculosis strains H37Ra and H37Rv and clinically isolated multidrug-resistant M. tuberculosis strains. Ten compounds d...

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Bibliografische gegevens
Gepubliceerd in:Medchemcomm
Hoofdauteurs: Zhang, Niu-niu, Liu, Zhi-yong, Liang, Jie, Tang, Yun-xiang, Qian, Lu, Gao, Ya-min, Zhang, Tian-yu, Yan, Ming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Royal Society of Chemistry 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096355/
https://ncbi.nlm.nih.gov/pubmed/30151083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00212f
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