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Design, synthesis, and biological evaluation of m-amidophenol derivatives as a new class of antitubercular agents

A series of m-amidophenol derivatives (6a–6l, 7a–7q, 9a, 9b, 12a–12c, 14 and 15) were designed and synthesized. Their antitubercular activities were evaluated in vitro against M. tuberculosis strains H37Ra and H37Rv and clinically isolated multidrug-resistant M. tuberculosis strains. Ten compounds d...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Zhang, Niu-niu, Liu, Zhi-yong, Liang, Jie, Tang, Yun-xiang, Qian, Lu, Gao, Ya-min, Zhang, Tian-yu, Yan, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096355/
https://ncbi.nlm.nih.gov/pubmed/30151083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00212f
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