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E-Cadherin Loss Accelerates Tumor Progression and Metastasis in a Mouse Model of Lung Adenocarcinoma

Metastatic disease is the primary cause of death of patients with lung cancer, but the mouse models of lung adenocarcinoma do not accurately recapitulate the tumor microenvironment or metastatic disease observed in patients. In this study, we conditionally deleted E-cadherin in an autochthonous lung...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Respir Cell Mol Biol
Prif Awduron: Sinkevicius, Kerstin W., Bellaria, Kelly J., Barrios, Juliana, Pessina, Patrizia, Gupta, Manav, Brainson, Christine Fillmore, Bronson, Roderick T., Kim, Carla F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096341/
https://ncbi.nlm.nih.gov/pubmed/29447458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0210OC
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