Archaeal Unfoldase Counteracts Protein Misfolding Retinopathy in Mice

Deregulation of cellular proteostasis due to the failure of the ubiquitin proteasome system to dispose of misfolded aggregation-prone proteins is a hallmark of various neurodegenerative diseases in humans. Microorganisms have evolved to survive massive protein misfolding and aggregation triggered by...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Brooks, Celine, Snoberger, Aaron, Belcastro, Marycharmain, Murphy, Joseph, Kisselev, Oleg G., Smith, David M., Sokolov, Maxim
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2018
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096037/
https://ncbi.nlm.nih.gov/pubmed/30012684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0905-18.2018
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