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lncRNA ZEB1-AS1 Was Suppressed by p53 for Renal Fibrosis in Diabetic Nephropathy

The role of p53 in renal fibrosis is still controversial, and its underlying mechanisms remain not clear. Here, we showed that the pharmacological inhibition and genetic deletion of p53 in proximal tubular cells can attenuate renal dysfunction, tubular epithelial disruption, and interstitial fibrosi...

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Библиографические подробности
Опубликовано в: :Mol Ther Nucleic Acids
Главные авторы: Wang, Juan, Pang, Jian, Li, Huiling, Long, Jie, Fang, Fang, Chen, Junxiang, Zhu, Xuejin, Xiang, Xudong, Zhang, Dongshan
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Gene & Cell Therapy 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095953/
https://ncbi.nlm.nih.gov/pubmed/30121551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.07.012
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