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lncRNA ZEB1-AS1 Was Suppressed by p53 for Renal Fibrosis in Diabetic Nephropathy

The role of p53 in renal fibrosis is still controversial, and its underlying mechanisms remain not clear. Here, we showed that the pharmacological inhibition and genetic deletion of p53 in proximal tubular cells can attenuate renal dysfunction, tubular epithelial disruption, and interstitial fibrosi...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Wang, Juan, Pang, Jian, Li, Huiling, Long, Jie, Fang, Fang, Chen, Junxiang, Zhu, Xuejin, Xiang, Xudong, Zhang, Dongshan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095953/
https://ncbi.nlm.nih.gov/pubmed/30121551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.07.012
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