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lncRNA ZEB1-AS1 Was Suppressed by p53 for Renal Fibrosis in Diabetic Nephropathy

The role of p53 in renal fibrosis is still controversial, and its underlying mechanisms remain not clear. Here, we showed that the pharmacological inhibition and genetic deletion of p53 in proximal tubular cells can attenuate renal dysfunction, tubular epithelial disruption, and interstitial fibrosi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther Nucleic Acids
Hauptverfasser: Wang, Juan, Pang, Jian, Li, Huiling, Long, Jie, Fang, Fang, Chen, Junxiang, Zhu, Xuejin, Xiang, Xudong, Zhang, Dongshan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095953/
https://ncbi.nlm.nih.gov/pubmed/30121551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.07.012
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