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p53 induces miR199a-3p to suppress SOCS7 for STAT3 activation and renal fibrosis in UUO
The role of p53 in renal fibrosis has recently been suggested, however, its function remains controversial and the underlying mechanism is unclear. Here, we show that pharmacological and genetic blockade of p53 attenuated renal interstitial fibrosis, apoptosis, and inflammation in mice with unilater...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5327480/ https://ncbi.nlm.nih.gov/pubmed/28240316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43409 |
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