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Molecular regulation of acute Tie2 suppression in sepsis
OBJECTIVE: Tie2 is a tyrosine kinase receptor expressed by endothelial cells (ECs) that maintains vascular barrier function. We recently reported that diverse critical illnesses acutely decrease Tie2 expression and that experimental Tie2 reduction suffices to recapitulate cardinal features of the se...
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| Publicado no: | Crit Care Med |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6095816/ https://ncbi.nlm.nih.gov/pubmed/29979219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000003269 |
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