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Identification of specific Tie2 cleavage sites and therapeutic modulation in experimental sepsis
Endothelial Tie2 signaling plays a pivotal role in vascular barrier maintenance at baseline and after injury. We previously demonstrated that a sharp drop in Tie2 expression observed across various murine models of critical illnesses is associated with increased vascular permeability and mortality....
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7447424/ https://ncbi.nlm.nih.gov/pubmed/32838837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59520 |
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