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Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche

Aging of hematopoietic stem cells (HSCs) is associated with a decline in their regenerative capacity and multi-lineage differentiation potential, contributing to the development of blood disorders. The bone marrow microenvironment has recently been suggested to influence HSC aging, but the underlyin...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Maryanovich, Maria, Zahalka, Ali H., Pierce, Halley, Pinho, Sandra, Nakahara, Fumio, Asada, Noboru, Wei, Qiaozhi, Wang, Xizhe, Ciero, Paul, Xu, Jianing, Leftin, Avigdor, Frenette, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095812/
https://ncbi.nlm.nih.gov/pubmed/29736022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0030-x
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