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The hematopoietic stem cell niche: from embryo to adult

Hematopoietic stem cells (HSCs) develop in discrete anatomical niches, migrating during embryogenesis from the aorta-gonad-mesonephros (AGM) region to the fetal liver, and finally to the bone marrow, where most HSCs reside throughout adult life. These niches provide supportive microenvironments that...

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Dettagli Bibliografici
Pubblicato in:Development
Autori principali: Gao, Xin, Xu, Chunliang, Asada, Noboru, Frenette, Paul S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825844/
https://ncbi.nlm.nih.gov/pubmed/29358215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.139691
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