Fetal liver hematopoietic stem cell niches associate with portal vessels

Whereas the cellular basis of the hematopoietic stem cell (HSC) niche in the bone marrow has been characterized, the nature of the fetal liver (FL) niche is not yet elucidated. We show that Nestin(+)NG2(+) pericytes associate with portal vessels, forming a niche promoting HSC expansion. Nestin(+)NG2...

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Publicat a:Science
Autors principals: Khan, Jalal A., Mendelson, Avital, Kunisaki, Yuya, Birbrair, Alexander, Kou, Yan, Arnal-Estapé, Anna, Pinho, Sandra, Ciero, Paul, Nakahara, Fumio, Ma’ayan, Avi, Bergman, Aviv, Merad, Miriam, Frenette, Paul S.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706788/
https://ncbi.nlm.nih.gov/pubmed/26634440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad0084
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