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Impact of Neurodegenerative Diseases on Drug Binding to Brain Tissues: From Animal Models to Human Samples
Drug efficacy in the central nervous system (CNS) requires an additional step after crossing the blood–brain barrier. Therapeutic agents must reach their targets in the brain to modulate them; thus, the free drug concentration hypothesis is a key parameter for in vivo pharmacology. Here, we report t...
Gorde:
| Argitaratua izan da: | Neurotherapeutics |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Springer International Publishing
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6095788/ https://ncbi.nlm.nih.gov/pubmed/29675823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-018-0624-5 |
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