Exploratory Application of Neuropharmacometabolomics in Severe Childhood Traumatic Brain Injury

OBJECTIVE: To employ metabolomics-based pathway and network analyses to evaluate the cerebrospinal fluid (CSF) metabolome after severe traumatic brain injury (TBI) in children, and the capacity of combination therapy with probenecid and N-acetylcysteine (NAC) to impact glutathione-related and other...

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Bibliografske podrobnosti
izdano v:Crit Care Med
Main Authors: Hagos, Fanuel T., Empey, Philip E., Wang, Pengcheng, Ma, Xiaochao, Poloyac, Samuel M., Bayır, Hülya, Kochanek, Patrick M., Bell, Michael J., Clark, Robert S. B.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095742/
https://ncbi.nlm.nih.gov/pubmed/29742587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000003203
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