A peripherally restricted cannabinoid 1 receptor agonist as a novel analgesic in cancer-induced bone pain

Many malignant cancers, including breast cancer, have a propensity to invade bones, leading to excruciating bone pain. Opioids are the primary analgesics used to alleviate this cancer-induced bone pain (CIBP) but are associated with numerous severe side effects, including enhanced bone degradation,...

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Detalhes bibliográficos
Publicado no:Pain
Main Authors: Zhang, Hong, Lund, Dominique M., Ciccone, Haley A., Staatz, William D., Ibrahim, Mohab M., Largent-Milnes, Tally M., Seltzman, Herbert H., Spigelman, Igor, Vanderah, Todd W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095738/
https://ncbi.nlm.nih.gov/pubmed/29781960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001278
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