A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss

AIMS: Cannabinoid CB(2) agonists have been shown to alleviate behavioral signs of inflammatory and neuropathic pain in animal models. AM1241, a CB(2) agonist, does not demonstrate central nervous system side-effects seen with CB(1) agonists such as hypothermia and catalepsy. Metastatic bone cancer c...

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Main Authors: Lozano, Alysia, Wright, Courtney, Vardanyan, Anna, King, Tamara, Largent-Milnes, Tally M., Nelson, Mark, Jimenez-Andrade, Juan Miguel, Mantyh, Patrick W, Vanderah, Todd W.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871326/
https://ncbi.nlm.nih.gov/pubmed/20176037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2010.02.014
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