Caricamento...

Subcutaneous Administration of Lyso-Phosphatidylserine Nanoparticles Induces Immunological Tolerance Towards Factor VIII in a Hemophilia A Mouse Model

A major complication with enzyme replacement therapy of Factor VIII (FVIII) in Hemophilia A (HA) is the development of anti-drug antibodies. Recently, we have shown that FVIII administration in the presence of heterogeneous phosphatidylserine (PS) nanoparticles derived from a natural source induces...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Int J Pharm
Autori principali: Glassman, Fiona Y., Balu-Iyer, Sathy V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095657/
https://ncbi.nlm.nih.gov/pubmed/29981412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2018.07.018
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !