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Amelioration of spinal cord injury in rats by blocking peroxynitrite/calpain activity

BACKGROUND: Spinal cord injury (SCI) is one of the leading causes of disability and chronic pain. In SCI-induced pathology, homeostasis of the nitric oxide (NO) metabolome is lost. Major NO metabolites such as S-nitrosoglutathione (GSNO) and peroxynitrite are reported to play pivotal roles in regula...

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Bibliografiska uppgifter
I publikationen:BMC Neurosci
Huvudupphovsmän: Khan, Mushfiquddin, Dhammu, Tajinder S., Singh, Inderjit, Singh, Avtar K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090709/
https://ncbi.nlm.nih.gov/pubmed/30103682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-018-0450-z
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