Carnosine selectively inhibits migration of IDH-wildtype glioblastoma cells in a co-culture model with fibroblasts

BACKGROUND: Glioblastoma (GBM) is a tumor of the central nervous system. After surgical removal and standard therapy, recurrence of tumors is observed within 6–9 months because of the high migratory behavior and the infiltrative growth of cells. Here, we investigated whether carnosine (β-alanine-l-h...

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Dettagli Bibliografici
Pubblicato in:Cancer Cell Int
Autori principali: Oppermann, Henry, Dietterle, Johannes, Purcz, Katharina, Morawski, Markus, Eisenlöffel, Christian, Müller, Wolf, Meixensberger, Jürgen, Gaunitz, Frank
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Primary Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090706/
https://ncbi.nlm.nih.gov/pubmed/30123089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-018-0611-2
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