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Pyruvate attenuates the anti-neoplastic effect of carnosine independently from oxidative phosphorylation

Here we analyzed whether the anti-neoplastic effect of carnosine, which inhibits glycolytic ATP production, can be antagonized by ATP production via oxidative phosphorylation fueled by pyruvate. Therefore, glioblastoma cells were cultivated in medium supplemented with glucose, galactose or pyruvate...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Oppermann, Henry, Schnabel, Lutz, Meixensberger, Jürgen, Gaunitz, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349879/
https://ncbi.nlm.nih.gov/pubmed/27811375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13039
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