Carnosine selectively inhibits migration of IDH-wildtype glioblastoma cells in a co-culture model with fibroblasts

BACKGROUND: Glioblastoma (GBM) is a tumor of the central nervous system. After surgical removal and standard therapy, recurrence of tumors is observed within 6–9 months because of the high migratory behavior and the infiltrative growth of cells. Here, we investigated whether carnosine (β-alanine-l-h...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Oppermann, Henry, Dietterle, Johannes, Purcz, Katharina, Morawski, Markus, Eisenlöffel, Christian, Müller, Wolf, Meixensberger, Jürgen, Gaunitz, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090706/
https://ncbi.nlm.nih.gov/pubmed/30123089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-018-0611-2
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