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Modulation of nuclear factor-κB signaling and reduction of neural tube defects by quercetin-3-glucoside in embryos of diabetic mice

BACKGROUND: Diabetes mellitus in early pregnancy increases the risk of birth defects in infants. Maternal hyperglycemia stimulates the expression of nitric oxide (NO) synthase 2 (NOS2), which can be regulated by transcription factors of the nuclear factor-κB (NF-κB) family. Increases in reactive nit...

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Bibliografski detalji
Izdano u:Am J Obstet Gynecol
Glavni autori: Tan, Chengyu, Meng, Fantong, Reece, E. Albert, Zhao, Zhiyong
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090545/
https://ncbi.nlm.nih.gov/pubmed/29733843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2018.04.045
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