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Effects of flexibility of the α2 chain of type I collagen on collagenase cleavage
Cleavage of collagen by collagenases such as matrix metalloproteinase 1 (MMP-1) is a key step in development, tissue remodeling, and tumor proliferation. The abundant heterotrimeric type I collagen composed of two α1(I) chains and one α2(I) chain is efficiently cleaved by MMP-1 at a unique site in t...
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| Yayımlandı: | J Struct Biol |
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| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6089644/ https://ncbi.nlm.nih.gov/pubmed/29763735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2018.05.002 |
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