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Collagen Gly missense mutations: Effect of residue identity on collagen structure and integrin binding
Gly missense mutations in type I collagen, which replace a conserved Gly in the repeating (Gly-Xaa-Yaa)(n) sequence with a larger residue, are known to cause Osteogenesis Imperfecta (OI). The clinical consequences of such mutations range from mild to lethal, with more serious clinical severity assoc...
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| Publicado no: | J Struct Biol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6089640/ https://ncbi.nlm.nih.gov/pubmed/29758270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2018.05.003 |
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