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Folding Delay and Structural Perturbations Caused by Type IV Collagen Natural Interruptions and Nearby Gly Missense Mutations

The standard collagen triple helix requires Gly as every third residue in the amino acid sequence, yet all nonfibrillar collagens contain sites where this repeating pattern is interrupted. To explore the effects of such natural interruptions on the triple helix, a 4- or 15-residue sequence from huma...

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Autors principals: Hwang, Eileen S., Brodsky, Barbara
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281714/
https://ncbi.nlm.nih.gov/pubmed/22179614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.269084
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