Increased expression of the thyroid hormone nuclear receptor TRα1 characterizes intestinal tumors with high Wnt activity

Our previous work demonstrated a key function of the thyroid hormone nuclear receptor TRα1, a T3-modulated transcription factor, in controlling intestinal development and homeostasis via the Wnt and Notch pathways. Importantly, increased expression of TRα1 in the intestinal epithelium in a mutated A...

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Publicado en:Oncotarget
Autores principales: Uchuya-Castillo, Joel, Aznar, Nicolas, Frau, Carla, Martinez, Pierre, Le Nevé, Clementine, Marisa, Laetitia, Penalva, Luiz O.F., Laurent-Puig, Pierre, Puisieux, Alain, Scoazec, Jean-Yves, Samarut, Jacques, Ansieau, Stephane, Plateroti, Michelina
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089551/
https://ncbi.nlm.nih.gov/pubmed/30123421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25741
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