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Overlapping open reading frames strongly reduce human and yeast STN1 gene expression and affect telomere function
The levels of telomeric proteins, such as telomerase, can have profound effects on telomere function, cell division and human disease. Here we demonstrate how levels of Stn1, a component of the conserved telomere capping CST (Cdc13, Stn1, Ten1) complex, are tightly regulated by an upstream overlappi...
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| Izdano u: | PLoS Genet |
|---|---|
| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6089452/ https://ncbi.nlm.nih.gov/pubmed/30067734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007523 |
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