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Overlapping open reading frames strongly reduce human and yeast STN1 gene expression and affect telomere function
The levels of telomeric proteins, such as telomerase, can have profound effects on telomere function, cell division and human disease. Here we demonstrate how levels of Stn1, a component of the conserved telomere capping CST (Cdc13, Stn1, Ten1) complex, are tightly regulated by an upstream overlappi...
Guardat en:
| Publicat a: | PLoS Genet |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6089452/ https://ncbi.nlm.nih.gov/pubmed/30067734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007523 |
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