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Telomeric Silencing of an Open Reading Frame in Saccharomyces cerevisiae

The endmost chromosome I ORF is silenced by a natural telomere position effect. YAR073W/IMD1 was found to be transcribed at much higher levels in sir3 mutants and when its adjacent telomere was removed from it. These results suggest that telomeres play a role in silencing actual genes.

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Bibliographische Detailangaben
Hauptverfasser: Barton, Arnold B., Kaback, David B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Copyright © 2006 by the Genetics Society of America 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1526490/
https://ncbi.nlm.nih.gov/pubmed/16582424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.058420
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