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Telomeric Silencing of an Open Reading Frame in Saccharomyces cerevisiae
The endmost chromosome I ORF is silenced by a natural telomere position effect. YAR073W/IMD1 was found to be transcribed at much higher levels in sir3 mutants and when its adjacent telomere was removed from it. These results suggest that telomeres play a role in silencing actual genes.
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Copyright © 2006 by the Genetics Society of America
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1526490/ https://ncbi.nlm.nih.gov/pubmed/16582424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.058420 |
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