A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells

Malaria parasites replicate within a parasitophorous vacuole (PV) in red blood cells (RBC). Progeny merozoites egress upon rupture of first the PV membrane (PVM) then poration and rupture of the RBC membrane (RBCM). Egress is protease-dependent1, but none of the effector molecules that mediate membr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Microbiol
Prif Awduron: Thomas, James A, Tan, Michele S Y, Bisson, Claudine, Borg, Aaron, Umrekar, Trishant R, Hackett, Fiona, Hale, Victoria L, Vizcay-Barrena, Gema, Fleck, Roland A, Snijders, Ambrosius P, Saibil, Helen R, Blackman, Michael J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089347/
https://ncbi.nlm.nih.gov/pubmed/29459732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-018-0111-0
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