A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells

Malaria parasites replicate within a parasitophorous vacuole (PV) in red blood cells (RBC). Progeny merozoites egress upon rupture of first the PV membrane (PVM) then poration and rupture of the RBC membrane (RBCM). Egress is protease-dependent1, but none of the effector molecules that mediate membr...

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Publicat a:Nat Microbiol
Autors principals: Thomas, James A, Tan, Michele S Y, Bisson, Claudine, Borg, Aaron, Umrekar, Trishant R, Hackett, Fiona, Hale, Victoria L, Vizcay-Barrena, Gema, Fleck, Roland A, Snijders, Ambrosius P, Saibil, Helen R, Blackman, Michael J
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089347/
https://ncbi.nlm.nih.gov/pubmed/29459732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-018-0111-0
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