An integrated functional genomics approach identifies the regulatory network directed by brachyury (T) in chordoma

Chordoma is a rare malignant tumour of bone, the molecular marker of which is the expression of the transcription factor, brachyury. Having recently demonstrated that silencing brachyury induces growth arrest in a chordoma cell line, we now seek to identify its downstream target genes. Here we use a...

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Vydáno v:J Pathol
Hlavní autoři: Nelson, Andrew C, Pillay, Nischalan, Henderson, Stephen, Presneau, Nadège, Tirabosco, Roberto, Halai, Dina, Berisha, Fitim, Flicek, Paul, Stemple, Derek L, Stern, Claudio D, Wardle, Fiona C, Flanagan, Adrienne M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089345/
https://ncbi.nlm.nih.gov/pubmed/22847733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4082
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