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Deubiquitination and stabilization of programmed cell death ligand 1 by ubiquitin‐specific peptidase 9, X‐linked in oral squamous cell carcinoma

BACKGROUND: The immune checkpoint protein programmed cell death ligand 1 (PD‐L1) binds to PD1 to promote tumor cell escape from the killing effect of the immune system. However, there are few studies on the regulatory mechanisms of PD‐L1 in tumors. Although PD‐L1 has been reported to undergo ubiquit...

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Dettagli Bibliografici
Pubblicato in:Cancer Med
Autori principali: Jingjing, Wu, Wenzheng, Guo, Donghua, Wen, Guangyu, Hou, Aiping, Zhou, Wenjuan, Wu
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089178/
https://ncbi.nlm.nih.gov/pubmed/29992764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1675
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