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Deubiquitination and stabilization of programmed cell death ligand 1 by ubiquitin‐specific peptidase 9, X‐linked in oral squamous cell carcinoma

BACKGROUND: The immune checkpoint protein programmed cell death ligand 1 (PD‐L1) binds to PD1 to promote tumor cell escape from the killing effect of the immune system. However, there are few studies on the regulatory mechanisms of PD‐L1 in tumors. Although PD‐L1 has been reported to undergo ubiquit...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Med
Hauptverfasser: Jingjing, Wu, Wenzheng, Guo, Donghua, Wen, Guangyu, Hou, Aiping, Zhou, Wenjuan, Wu
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089178/
https://ncbi.nlm.nih.gov/pubmed/29992764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1675
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