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No pharmacokinetic interactions between candesartan and amlodipine following multiple oral administrations in healthy subjects

PURPOSE: To evaluate the pharmacokinetics and pharmacodynamics of candesartan and amlodipine in the absence and presence of each other in healthy subjects. METHODS: This study consisted of two parts: part 1, the effect of amlodipine on candesartan; part 2, the effect of candesartan on amlodipine. Ea...

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Publicat a:Drug Des Devel Ther
Autors principals: Kim, Jung-Ryul, Kim, Seokuee, Huh, Wooseong, Ko, Jae-Wook
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089104/
https://ncbi.nlm.nih.gov/pubmed/30127595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S172568
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