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Improving small molecule virtual screening strategies for the next generation of therapeutics
The new generation of post-genomic targets, such as protein-protein interactions (PPIs), often require new chemotypes not well represented in current compound libraries. This is one reason for why traditional high throughput screening (HTS) approaches are not more successful in delivering medicinal...
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| Udgivet i: | Curr Opin Chem Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6089075/ https://ncbi.nlm.nih.gov/pubmed/29920436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2018.06.006 |
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