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PARP inhibitors for Homologous Recombination- Deficient Prostate Cancer

INTRODUCTION: Prostate adenocarcinoma represents a leading cause of cancer-related mortality. Increased emphasis on understanding the molecular basis of prostate cancer has identified a substantial burden of homologous recombination (HR) pathway mutations, which are enriched in castrate-resistant di...

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Detalhes bibliográficos
Publicado no:Expert Opin Emerg Drugs
Main Authors: Christenson, Eric S., Antonarakis, Emmanuel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6088797/
https://ncbi.nlm.nih.gov/pubmed/29595348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728214.2018.1459563
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