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PARP Inhibitors as a Therapeutic Agent for Homologous Recombination Deficiency in Breast Cancers
Poly (ADP-ribose) polymerases (PARPs) play an important role in various cellular processes, such as replication, recombination, chromatin remodeling, and DNA repair. Emphasizing PARP’s role in facilitating DNA repair, the PARP pathway has been a target for cancer researchers in developing compounds...
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| Publicado no: | J Clin Med |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6517993/ https://ncbi.nlm.nih.gov/pubmed/30934991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8040435 |
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