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PARP Inhibitors in Metastatic Prostate Cancer: Evidence to Date
Poly (ADP-ribose) polymerase inhibitors (PARPi) are a unique class of antineoplastic agents that function by inducing synthetic lethality. Synthetic lethality occurs when PARPi and either another agent or an underlying genetic alteration together lead to overwhelming DNA damage and ultimately cell d...
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| Publicado no: | Cancer Manag Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7489946/ https://ncbi.nlm.nih.gov/pubmed/32982407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S227033 |
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