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C797S Resistance: The Undruggable EGFR Mutation in Non-Small Cell Lung Cancer?
[Image: see text] The first evidence of osimertinib resistance mediated by the epidermal growth factor receptor (EGFR) mutation C797S was reported three years ago. Since then, no major breakthroughs have been achieved to target the clinically relevant mutant variant that impedes covalent bond format...
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| Wydane w: | ACS Med Chem Lett |
|---|---|
| Główni autorzy: | , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Chemical
Society
2018
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6088362/ https://ncbi.nlm.nih.gov/pubmed/30128066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00314 |
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