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EGFR C797S as a Resistance Mechanism of Lazertinib in Non-small Cell Lung Cancer with EGFR T790M Mutation

The non-small cell lung cancer with activating epidermal growth factor receptor (EGFR) mutation eventually acquires resistant to either first or second-generation EGFR tyrosine kinase inhibitor (TKI). As the following option, targeting EGFR T790M with third-generation EGFR TKI is now established as...

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Pubblicato in:Cancer Res Treat
Autori principali: Park, Sehhoon, Ku, Bo Mi, Jung, Hyun Ae, Sun, Jong-Mu, Ahn, Jin Seok, Lee, Se-Hoon, Park, Keunchil, Ahn, Myung-Ju
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Cancer Association 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577810/
https://ncbi.nlm.nih.gov/pubmed/32599977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2020.278
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