Culture-Expanded Human Invariant Natural Killer T Cells Suppress T-Cell Alloreactivity and Eradicate Leukemia

Graft-versus-host disease (GVHD) is a major cause of significant morbidity and mortality after allogeneic hematopoietic cell transplantation (HCT). Invariant natural killer T (iNKT) cells are potent regulators of immune responses, protect from lethal GVHD, and promote graft-versus-leukemia effects i...

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Udgivet i:Front Immunol
Main Authors: Schmid, Hannes, Schneidawind, Corina, Jahnke, Simona, Kettemann, Felix, Secker, Kathy-Ann, Duerr-Stoerzer, Silke, Keppeler, Hildegard, Kanz, Lothar, Savage, Paul B., Schneidawind, Dominik
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6088196/
https://ncbi.nlm.nih.gov/pubmed/30127790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01817
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