Combined Drug Resistance Mutations Substantially Enhance Enzyme Production in Paenibacillus agaridevorans

This study shows that sequential introduction of drug resistance mutations substantially increased enzyme production in Paenibacillus agaridevorans. The triple mutant YT478 (rsmG Gln225→stop codon, rpsL K56R, and rpoB R485H), generated by screening for resistance to streptomycin and rifampin, expres...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Funane, Kazumi, Tanaka, Yukinori, Hosaka, Takeshi, Murakami, Kiriko, Miyazaki, Takatsugu, Shiwa, Yuh, Gibu, Shigehachi, Inaoka, Takashi, Kasahara, Ken, Fujita, Nobuyuki, Yoshikawa, Hirofumi, Hiraga, Yoshikazu, Ochi, Kozo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6088162/
https://ncbi.nlm.nih.gov/pubmed/29866810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00188-18
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